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Question

In a DNA molecule, the phosphate group is attached to ____carbon of the sugar residue of its own nucleotide and _____ carbon of the sugar residue of the next nucleotide by ____bonds.

A
5', 3', phosphodiester
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B
5', 3', glycosidic
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C
3', 5', phosphodiester
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D
3', 5', glycosidic
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Solution

The correct option is A 5', 3', phosphodiester
A deoxyribonucleotide of DNA is formed by cross- linking of three chemicals - deoxyribose sugar (C5H10O4),a nitrogen base and phosphoric acid (H3PO4). The backbone of a DNA strand is build up of alternate deoxyribose and phosphoric acid groups. The phosphate group is connected to carbon 5 of the sugar residue of its own nucleotide and carbon 3 of the sugar residue of the next nucleotide by phosphodiester bonds.
So, the correct answer is '5', 3', phosphodiester'.

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