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Question

In a Mendelian monohybrid cross, the F2 generation shows identical genotypic and phenotypic ratios. What does it tell us about the nature of alleles involved? Justify your answer.

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Solution

Monohybrid cross

Monohybrid cross is a cross between parents having different alleles at a single gene locus for a particular trait. In a Mendelian monohybrid cross, the F2 generation shows non-identical genotypic (1:2:1) and phenotypic (3:1) ratios.

Incomplete dominance

The alleles exhibiting incomplete dominance lead to the blending of contrasting traits in heterozygous condition. A cross between true-breeding varieties produces heterozygous progeny whose phenotype is different from that of the parents.

Example of incomplete dominance

Example of four o'clock plant (Mirabilis jalapa):

A cross between a pure red flowered plant (RR) and pure white flowered plant (rr) yields hybrid pink flowered plant (Rr) due to incomplete dominance.

Here, the dominant allele R is not able to completely mask the effect of the recessive allele r. So, they show identical genotypic and phenotypic ratios in F2 generation, that is 1:2:1.



F1 generation of incomplete dominance

Cross between red (RR) and white (rr) flowered plants produced all pink progeny (Rr) in F1 generation.
R r
R Rr
Pink
Rr
Pink
R Rr
Pink
Rr
Pink

F2 generation of incomplete dominance

Cross between two hybrid pink (Rr) flower plants produces red (RR), pink (Rr) and white flower (rr) plants in F2 generation.
R r
R RR
Red
Rr
Pink
r Rr
Pink
rr
White

Phenotype and genotype in F2 generation

Phenotype and genotype in F2 generation are as follows:
Characteristics Pure red flower
(RR)
Pink flower
(Rr)
Pure white flower
(rr)
Genotype 1 2 1
Phenotype 1 2 1

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