Question

In a person pars details part of the pituitary gland is not producing hormones in sufficient quantities explain the effects its produce with respect to the different hormone.

Answer 1

Pars distalis or anterior pituitary produce growth hormone (GH), luteinizing hormone (LH), follicular stimulating hormone (FSH), adrenocorticotropic hormone (ACTH), prolactin(PRL), Melanocyte-Stimulating Hormone (MSH) and Thyroid Stimulating Hormone (TSH).

Following are symptoms of insufficient production of anterior pituitary hormones:-

1. Growth hormone deficiency: in growing children, growth hormone deficiency results in short stature and/or very slow growth rates. In older children, the symptoms of growth hormone deficiency are harder to define but include low muscle mass, weaker bones, and lower energy levels.
   
2. ACTH deficiency: this is also called central adrenal insufficiency as the adrenal glands do not make enough of the stress hormone cortisol. This condition can be life-threatening if not recognized and treated properly. Cortisol is critical on a daily basis but especially when we are sick and stressed. ACTH deficiency can result in low blood pressure, weakness, dehydration, abdominal pain, weight loss, and difficulty in recovering from illnesses or surgeries.
   
3. Gonadotropin deficiency: FSH (follicular stimulating hormone) and LH (luteinizing hormone) are responsible for initiating and maintaining puberty. These hormones stimulate the testes to make testosterone in boys and the ovaries to make estrogen in girls. Deficiencies in FSH and LH can result in a failure of puberty to start or a disruption in normal pubertal progression.
   
4. TSH deficiency: hypothyroidism (low thyroid hormone levels) results when there is not enough TSH made to stimulate the thyroid gland to produce thyroid hormone. Hypothyroidism can result in fatigue, constipation, dry skin, brittle hair, poor growth, feeling cold all the time, and disruptions to normal periods in girls.
   
5. MSH deficiency: Melanocyte-stimulating hormone deficiency can cause increased inflammation, pain, and sleeping problems, as well as a reduction in the levels of anti-diuretic hormone, which causes thirst and frequent urination.