Question

In a regularly cycling human female, which can be the root cause of menstrual failure?

• A. Maintenance of high titre of sex hormones
• B. Fertilisation of ovum
• C. Maintenance of hypertrophic endometrial lining
• D. Retention of well-developed corpus luteum

Answer 1

The correct option is B Fertilisation of ovum

Menstrual cycle
The cyclic changes that occur in the ovaries and the lining of the uterus in the female reproductive system of primates are called the menstrual cycle. Examples include humans, monkeys, etc. The average menstrual cycle is 28 days long.

Causes of menstrual failure
The main cause of menstrual failure, in a regularly cycling human female, is as follows: The fertilisation of the ovum leads to the retaining of the corpus luteum in the ovary. The Corpus luteum secretes progesterone that finally prevents the maturation of another follicle in the ovary. This causes the temporary stoppage of menstruation.

Hypertrophic endometrium
The unusual thickening of the endometrium of the uterus is called hypertrophic endometrium. It may be due to the presence of high amounts of estrogen or not enough progesterone.

Final answer
(A) Fertilisation of ovum