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B
Females in response to oestrogen
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C
Both males and females in response to androgen
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D
Both males and females in response to oestrogen
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Solution
The correct option is B Both males and females in response to androgen
Androgens increase in both boys and girls during puberty. Androgens make the skin's oil glands get larger and make more sebum. Androgens also can increase because of hormonal changes related to pregnancy or starting or stopping birth control pills.
Genetics may also matter. If your parents had acne, you may have inherited that tendency. So the correct answer is 'Both males and females in response to androgen'.