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Question

In an experiment, DNA is treated with a compound which tends to place itself amongst the stacks of nitrogenous base pairs. As a result of this, the distance between two consecutive bases increases, from 0.34 nm to 0.44 nm. Calculate the length of the DNA double helix (which has 2×109 bp) in the presence of a saturating amount of this compound.

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Solution

Formula:

Length of the DNA double helix can be calculated by the formula = Number of base pairs in the double helix × Distance between two consecutive base pairs.

Calculation of length of DNA double helix:

Number of base pairs in the double helix =2×109 bp

Distance between two consecutive base pairs =0.44 nm=0.44×109 m

Length of the DNA double helix in the presence of compound =2×109×0.44×109

=0.88 m

Final answer:

0.88 m

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