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Question

In ATP, the high energy bond is the one which links

A
Adenine with ribose
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B
Ribose with phosphate
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C
Adenine with phosphate
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D
Phosphate to phosphate
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Solution

The correct option is D Phosphate to phosphate
ATP stands for Adenosine Tri-Phosphate. Adenine is attached to first or alpha phosphate through an ester bond formed between the phosphoric acid and hydroxyl group present at the carbon atom number five of the sugar. None of these bonds are high energy bonds because these can be produced relatively easily to form AMP (Adenosine Mono Phosphate). Next, another molecule of phosphoric acid reacts with the alpha phosphorous of AMP and attaches through an acid anhydride bond formed between two acids, thus forming ADP (Adenosine Di-Phosphate). A similar reaction will give rise to ATP (Adenosine Tri-Phosphate) in a similar fashion. The hydrolysis of ATP releases energy as the third phosphate is transferred to the another molecule and bond between second and third phosphate breaks to release energy as it is the high energy bond.

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