The correct option is A In human beings, Y chromosome is active in sex determination.
The ratio of X chromosmes to the number of sets of autosomes determine the sex in Drosophila. Here, presence or absence of "Y-chromosome" does not affect the sex of the organism. In human, presence or absence of "Y-chromosome" determine the sex. That's why, the XXY condition leads to femaleness in Drosophila but in human beings the same condition leads to Klinefelter's syndrome in male. Option A is correct answer.