Question

In exclusion chromatography ___________ sized particles are eluted first.

• A. large
• B. middle
• C. small
• D. all are eluted with same speed

Answer 1

The correct option is A large

Exclusion chromatography is a separation technique used to separate molecules on the basis of size and shape.
In this technique, large molecules separate first, unlike other techniques.
It is widely applicable to purification or desalting of proteins in complex samples such as blood, etc.