In feedback inhibition mechanism to control the rate of a metabolic pathway, the end product of the pathway acts as a
In feedback inhibition mechanism to control the rate of a metabolic pathway, the end product of the pathway acts as a
The correct option is C Allosteric inhibitor
The correct option is option (C):
Explanation of the correct option:
- Feedback inhibition is a type of allosteric regulation.
- In feedback inhibition, the enzymes regulate the reaction and the end product act as the inhibitor of this enzyme.
- Excess end product of the reaction enters and binds to the allosteric site of the initiator enzyme.
- By binding to an allosteric site, an allosteric inhibitor changes the protein conformation in the active site of the enzyme and change the shape of the active site.
Explanation of the incorrect option:
Option (A):
Competitive inhibitor compete with the substrate to bind with the active site of enzyme.
Option (B):
Irreversible inhibitors bind to the enzyme covalently or noncovalently and disassociate from it very slowly.
Option (D):
Binding of the Cooperative molecule occurs when the number of binding sites occupied by a given type of ligand is a nonlinear function of the ligand's concentration.
Final answer: In the feedback inhibition mechanism to control the rate of a metabolic pathway, the end product of the pathway acts as an allosteric inhibitor.
Allosteric inhibitor
The correct option is option (C):
Explanation of the correct option:
- Feedback inhibition is a type of allosteric regulation.
- In feedback inhibition, the enzymes regulate the reaction and the end product act as the inhibitor of this enzyme.
- Excess end product of the reaction enters and binds to the allosteric site of the initiator enzyme.
- By binding to an allosteric site, an allosteric inhibitor changes the protein conformation in the active site of the enzyme and change the shape of the active site.
Explanation of the incorrect option:
Option (A):
Competitive inhibitor compete with the substrate to bind with the active site of enzyme.
Option (B):
Irreversible inhibitors bind to the enzyme covalently or noncovalently and disassociate from it very slowly.
Option (D):
Binding of the Cooperative molecule occurs when the number of binding sites occupied by a given type of ligand is a nonlinear function of the ligand's concentration.
Final answer: In the feedback inhibition mechanism to control the rate of a metabolic pathway, the end product of the pathway acts as an allosteric inhibitor.
