Question

In gene therapy, DNA is inserted into a cell to compensate for

• A. Mutant alleles
• B. Absence of plasmids
• C. Lack of copy DNA
• D. None of the above

Answer 1

Answer: (A)

Mutant alleles

Gene therapy can be used to add the external DNA to the genome to replace a missing gene product, gene targeting to correct mutant alleles or to treat dominantly acting diseases via antisense RNA expression or the expression of intracellular antibodies. If the mutated gene makes a faulty protein or no protein, gene therapy introduces a normal copy of the gene, via a vector, to restore the function of the gene to produce a functional protein.

Thus, the correct answer is option A.