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Question

In genetic fingerprinting, the 'probe' refers to a radioactively labelled

A
Double-stranded RNA molecule
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B
Double-stranded DNA molecule
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C
Single-stranded DNA molecule
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D
Single-stranded RNA molecule
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Solution

The correct option is C Single-stranded DNA molecule
A probe can be defined as a labeled sequence of DNA or RNA that is used to identify the specific sequence of nucleotides in the DNA strand. These probes can be synthesized in the laboratory, with a sequence complementary to the target DNA sequence. They are radiolabeled so that their presence in the target DNA can be traced easily. These probes are single-stranded to allow their base-pairing with the target DNA strand. Hence, the correct answer is the option C.

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