The correct option is C Emphysema
Emphysema gradually damages the air sacs (alveoli) in your lungs, making you progressively shorter of breath. In emphysema, the inner walls of the air sacs weaken and eventually rupture - creating one larger air space instead of many small ones. This reduces the surface area of the lungs and, in turn, the amount of oxygen that reaches the bloodstream.
Thus, the correct answer is option (C), 'Emphysema'.