In how many of the distinct permutations of the letters in MISSISSIPPI do the four 'I's not come together?
Total letters of the word MISSISSIPPI = 11.
Here M=1, I=4, S=4 and P=2
∴ Number of permutations = 11!4 ! 4 ! 2 !
= 11×10×9×8×7×6×5×4!4!×4×3×2×1×2×1
= 34650
When the four 'I's come together, then it becomes one letter so total number of letters in the word when all I"s come together = 8.
∴ Number of permutations
= 8!4!2!=8×7×6×5×4!4!×2×1=840
Number of permutations when four I"s do not come together
= 34650−840=33810.