Question

In how many steps, glycolysis can be regulated?

• A. One
• B. Two
• C. Three
• D. Four

Answer 1

Answer: (C)

Three

Glycolysis is the process of breakdown of glucose into pyruvate to extract energy for various cellular metabolic processes. Enzymes that catalyze the three steps of glycolysis have very large negative G value, hexokinase (or glucokinase) for step 1, phosphofructokinase for step 3, and pyruvate kinase for step 10, are the regulatory steps for allosteric enzyme regulation. Generally, enzymes that catalyzing irreversible steps in the metabolic pathway have the potential for regulatory control because there is some blockage elsewhere in a pathway that leads to the accumulation of intermediates.

So, the correct answer is 'Three'.