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Question

In human females at the time of birth there are two million ova. How many of them normally reach maturity in the course of normal reproductive life?

A
500
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B
1000
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C
2000
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D
5000
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Solution

The correct option is A 500
Each ovary contains approximatley 2 million immature ova which were formed during the first 5 months of intra-uterine life. Throughout the life, the vast majority of the follicles will die off through a process called as atresia. Atresia begins at birth and continues throughout the course of the woman's reproductive life. When the woman reaches puberty and starts to menstruate, only about 400,000 follicles remain. With each menstrual cycle, a thousand follicles are lost and only one lucky little follicle will mature into an ovum, which is released into the fallopian tube, It means out of 1-2 million follicles, only about 400-500 will ever mature.

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