Question

In hybridoma technology.

• A. B-cells are fused with myeloma cells
• B. T-cells are fused with myeloma cells
• C. B-cells are fused with T-cells
• D. None of the above

Answer 1

The correct option is A B-cells are fused with myeloma cells

In hybridoma technology antibody producing B cells are fused with myeloma cells. These hybrid cells therefore acquire the capability to generate antibodies and also have the ability to live on indefinitely as it is a hybrid of myeloma cell. Hence, they are able to generate a large number of monoclonal antibodies.

So, the correct answer is 'B-cells are fused with myeloma cells'