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Types of Hormones

In Insulin mo...

Question

In Insulin molecule, there are two chains A and B. "A" contains "X" amino acids & "B" contains "Y" amino acids. The values of X and Y are:

A

21, 31

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B

28, 26

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C

21, 30

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D

32, 34

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Solution

The correct option is C 21, 30
The human insulin protein is composed of 51 amino acids. It is a dimer of an A-chain, consisting of 21 amino acids and a B-chain, consisting of 30 amino acids, linked together by disulphide bonds.

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Q. Total amino acids in insulin (bovine) are 51 in polypeptide chains A and B. How many amino acids are there in chain A?

Q. Assertion :Insulin is a globular protein. Reason: It has two polypeptide chains with 21 and 30 amino acids joined by sulphur bridges connecting cysteine amino acid on the two chains.

Q. Human insulin contains how many amino acids on B chain?

Q. Which of the following statements regarding the structure of proinsulin and mature insulin are not correct?
(i) Proinsulin is made up of three polypeptide chains A, B, and C.
(ii) C-polypeptide chain with 33 amino acids is removed prior to insulin formation.
(iii) Mature insulin is made up of 51 amino acids and arranged in two polypeptide chains-A and B.
(iv) Polypeptide chain A has 30 amino acids and polypeptide chain B has 21 amino acids.
(v) Polypeptide chains A and B are interconnected by only one S-S linkage.

Q. A compound which contains both ______ and ______ is called amino acid. The amino acids in polypeptide chain are joined by ______ bonds.

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