Question

In Kreb's cycle, guanosine triphosphate is formed during the conversion of

• A. Isocitrate to oxalosuccinate.
• B. Oxalosuccinate to $\alpha$-ketoglutarate.
• C. Succinyl Co-A to succinate.
• D. Fumarate to malate.

Answer 1

The correct option is C Succinyl Co-A to succinate.

Succinyl-CoA is a high energy compound formed during Kreb cycle by oxidative decarboxylation of alpha-ketoglutarate. The energy released during breakage of thioester bond of succinyl-CoA is used to drive the synthesis of GTP from GDP. This reversible reaction is catalysed by succinyl-CoA synthetase.

So, the correct answer is option C.