In Krebs cycle, second decarboxylation occurs during
A
Pyruvate Acetyl CoA
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B
-Ketoglutarate Succinyl CoA
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C
Oxalosuccinic acid -Ketoglutarate
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D
Malic acid Fumaric acid
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Solution
The correct option is B -Ketoglutarate Succinyl CoA In Krebs' cycle, decarboxylation occurs twice during the completion of one cycle. Second decarboxylation occurs when ketoglutarate (5) is converted to succinyl CoA (4 C) by ketoglutarate dehydrogenase liberating CO2.