Question

In Krebs's cycle, the conversion of succinyl CoA to succinic acid requires?

• A. Acetyl CoA$+$GDP$+$ip
• B. CoA$+$GTP$+$ip
• C. Acetyl CoA$+$GTP$+$ip
• D. GDP$+$ip

Answer 1

The correct option is A Acetyl CoA$+$GDP$+$ip

In eukaryotes, the citric acid cycle takes place in the matrix of the mitochondria, just like the conversion of pyruvate to acetyl CoA. In prokaryotes, these steps both take place in the cytoplasm. The citric acid cycle is a closed loop; the last part of the pathway reforms the molecule used in the first step. the CoA of succinyl CoA is replaced by a phosphate group, which is then transferred to ADP to make ATP. In some cells,GDP—guanosine diphosphate—is used instead of ADP, forming GTP—guanosine triphosphate—as a product. The four-carbon molecule produced in this step is called succinate.

So the correct option is 'acetyl CoA + GTP + ip'.