Question

In mammals, the release of pancreatic juice from the pancreas is triggered by

• A. secretin
• B. trypsinogen
• C. cholecystokinin
• D. enterokinase

Answer 1

The correct option is A secretin

Secretin, secreted by the epithelium of the duodenum, stimulates the secretion of pancreatic juice. In the pancreas, it also stimulates the release of bicarbonates into the pancreatic juice. In the liver, it stimulates the secretion of bile. In the stomach, it inhibits gastric secretion and motility.

Cholecystokinin (pancreozymin) is secreted by the epithelium of the entire small intestine. In the pancreas, it stimulates the release of pancreatic juice. In the gallbladder, it stimulates the release of bile.

Trypsinogen is an inactive form of enzyme (proenzyme) which is acted upon by another enzyme enterokinase and converted into its active form trypsin.