In mitosis, splitting of chromatids up to the centromere takes place in
A
Prophase
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B
Metaphase
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C
Anaphase
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D
Telophase
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Solution
The correct option is C Anaphase The anaphase is marked by division of centromere and contraction of spindle fibers which in turn cause splitting of chromosome and movement of sister chromatids towards the opposite poles. so, the correct answer is option C.