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Question

In muscles, from three molecules of glucose, two are completely oxidized and one is incompletely oxidized (anaerobic) then, what will be the number of total NAD+ molecules utilized?

A
20
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B
10
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C
14
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D
8
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Solution

The correct option is A 20
NAD+ is consumed only in aerobic respiration. Only two of the three glucose molecules were oxidized completely (aerobic respiration). Complete oxidation of glucose to carbon dioxide requires a total of 10 NAD+; conversion of glucose to 2 molecules of pyruvate (Glycolysis) 2 NAD+ are utilized. during conversion of 2 molecules of pyruvate to 2 molecules of acetylCoA, 2 molecules of NAD+ and finally for the oxidation of each acetylCoA molecule 3 NAD+ molecules are consumed (Kreb's cycle). Thus a total of 10 NAD+ are consumed for the complete oxidation of 1 glucose. Thus, the correct option is A

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