In presence of malonate, which step in the kreb cycle will be inhibited?

Malate to oxaloacetate

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Alpha ketogluterate to succinyl co-A

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Succinate to fumerate

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Citrate to alpha keto gluterate

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Solution

The correct option is C
Succinate to fumerate

Malonate inhibits succinate dehydrogenase which helps in conversion of succinate to fumerate. Hence the step involving conversion of succinate to fumerate will be blocked.

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Which molecule will combine with the four-carbon oxaloacetate in the Krebs cycle to form the six-carbon citrate?

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