Question

In the anaerobic reaction of muscle, lactic acid is produced which causes painful tiredness. Where and by which mechanism lactic acid is catabolized?

• A. In muscle by monokinase action
• B. In muscle by Lohmans reaction
• C. In liver by Cori cycle
• D. In liver by phosphogen reaction

Answer 1

Answer: (C)

In liver by Cori cycle

• Generally, the glucose undergoes metabolism in the presence of oxygen to form ATP (Adenosine triphosphate) which is essential for the muscle contraction but during strenuous exercise, the body cannot meet the oxygen demand and the glucose undergoes metabolism in the absence of oxygen which results in the formation and accumulation of lactic acid.
  
• This accumulated lactic acid is moved to the liver and converted into glycogen thorough Cori cycle.
• Cori cycle takes place in the liver.
• Hence In the anaerobic reaction of muscle, lactic acid is produced which causes painful tiredness. The lactic acid accumulated is catabolized by the mechanism of the Cori cycle in the liver.
• So, the correct answer is 'In liver by Cori cycle'