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Question

In the case of X-linked diseases, males who possess the gene for an unhealthy trait are:


A

affected

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B

carriers

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C

normal

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D

either A or B

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Solution

The correct option is A

affected


Sex linked disorders can be linked to either the X chromosome or the Y chromosome. X-linked disorders are those disorders of the X-chromosome. Since males have a single X-chromosome, if they have the defective gene, they will be affected as they do not have a healthy copy of the gene (healthy allele) to mask the defective allele. However, females having one copy of the defective gene on X-chromosome become carriers since they have a healthy copy of the gene to mask it.

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