In the clotting mechanism pathway, thrombin activates factors ____________.
A
VIII, X, V
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B
XI, VIII, X
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C
XI, IX, X
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D
XI, VIII, V
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Solution
The correct option is D XI, VIII, V Thrombin is the principal enzyme of hemostasis. It catalyzes the conversion of fibrinogen to fibrin and activates procoagulant factors V, VIII, XI, and XIII.