Question

In the given figure curve shows percentage saturation of haemoglobin with $O_2$ is plottedagainst $p{O}_2$. This curve is highly useful instudying the effect of which factors on binding of $O_2$ with haemoglobin?

• A. Carbonic anhydrase
• B. $pC{O}_2$
• C. $H^{+}$concentration
• D. Both b and c

Answer 1

The correct option is D Both b and c

This curve is called the oxygen dissociation curve and is highly useful in studying the effect of factors like $pC{O}_2$, $H^{+}$ concentration, etc. on binding of $O_2$ with haemoglobin. In the alveoli, where there is high $p{O}_2$, low $pC{O}_2$, lesser $H^{+}$ concentration and lower temperature, the factors are all favourable for the formation of oxyhaemoglobin, whereas in the tissues, where low $p{O}_2$, high $pC{O}_2$, high $H^{+}$ concentration and higher temperature exist, the conditions are favourable for dissociation of oxygen from the oxyhaemoglobin.