The correct option is
A RQSP
The proper sequence is RQSP. Let us see why.
The sentence starts with, 'His uncle', which is the subject. The clause (R) i.e 'who was a self-made man' describes the subject. Hence, it has to immediately follow the subject. Hence, the first part of the sentence is: 'His uncle, who was a self-made man'.
The first part of the sentence has to be followed by the verb. The answer to the question, 'What did his uncle do'? is given in part (Q) i.e 'always advised his son'. Hence, (Q) follows (R).
The phrase (S) i.e 'to depend on his own efforts' refers to what 'his uncle advised his son'. So, it has to follow (R). The final part left is (P) i.e 'for success in life'. This phrase refers to the reason for (S). i.e why the son has to depend on his own efforts. Hence, (P) follows (S).
So, the correct sentence is: 'His uncle, (R) who was a self-made man, (Q) advised his son, (S) to depend on his own efforts (P) for success in life'.
Hence, option B i.e RQSP is correct and the other options A, C and D are incorrect.