Question

In the Hofmann bromamide degradation reaction, the number of moles of $NaOH$ and ${Br}_2$ used per mole of amine produced are:

• A. four moles of $NaOH$ and two moles of ${Br}_2$
• B. two moles of $NaOH$ and two moles of ${Br}_2$
• C. four moles of $NaOH$ and one mole of ${Br}_2$
• D. one mole of $NaOH$ and one mole of ${Br}_2$

Answer 1

The correct option is C four moles of $NaOH$ and one mole of ${Br}_2$

Primary Amines can be prepared by Hofmann degradation. Hofmann bromamide degradation reaction.

4 moles of NaOH and one mole of Br2 is required during the production of one mole of amine during Hoffmann's bromamide degradation reaction.

$R-\stackrel{\begin{array}{c}\text{O}\\ ||\end{array}}{C}-N{H}_2+B{r}_2+4NaOH\to R-N{H}_2+K_{2}C{O}_3+2NaBr+2H_{2}O$