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Question

In the life-cycle of Plasmodium vivax, some stages may survive for long periods in liver as dormant stages known as

A
Hypnozoites
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B
Cryptozoites
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C
Sporozoites
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D
Merozoites
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Solution

The correct option is B Hypnozoites
Plasmodium vivax is the most widespread malaria parasite. It has a dormant stage in the human liver, which makes it difficult to eradicate. The dormant stage maximizes the possibility for the parasite to reach the vector for sexual reproduction. The sporozoites invade the cells of the salivary gland in the vector and the hepatocytes in the human. Some of the sporozoites develop into hypnozoites in the human liver. The hypnozoite activates when it recognizes the same Anopheles specific protein, which it had previously recognized as a sporozoite to invade the salivary gland in the vector. The hypnozoite activates upon the bodily reaction by the human on a bite by an Anopheles female.

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