Question

In the MN-blood grouping system of a population, if the allele frequencies of M and N alleles are 0.6 and 0.4 respectively, the expected frequency of individuals bearing the MN-blood group is likely to be

• A. 48%
• B. 36%
• C. 16%
• D. 24%

Answer 1

The correct option is A 48%

According to the Hardy–Weinberg principle, if the allele frequencies in a population with two alleles at a locus are p and q, then the expected genotype frequencies are $p^2$, $2pq$ and $q^2$ .

At Hardy–Weinberg equilibrium, $(p+q{)}^2$= $p^2$ + $2pq$ + $q^2$ = $1$

Frequency of MN = $2pq$
= $2\times 0.6\times 0.4$
Expected frequency of MN group = $(2\times 0.6\times 0.4)$ x $100$ = $48$ %

So the correct option is '$48$ %'.