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Question

In the thin filament of skeletal muscle fiber, a small globular protein that masks the active sites on the actin, is

A
G-actin
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B
Actin
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C
Tropomyosin
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D
Troponin
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E
Myosin
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Solution

The correct option is D Troponin
The thin filament of skeletal muscle fiber is composed of three distinct proteins, i.e. actin, tropomyosin, and troponin. Troponin inhibits the actin-myosin interaction. The binding of calcium to the troponin unmasks the myosin binding active sites on actin. Tropomyosin is a fibrous molecule that attaches to actin in the groove between its filaments. G-actin is the monomer of the actin filament.


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