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Question

In tryptophan operon, a repressor consists of co-repressor and apo-repressor. These two consist of

A
Protein and tryptophan
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B
RNA and protein
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C
Tryptophan and protein
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D
RNA and tryptophan
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Solution

The correct option is B Tryptophan and protein
When tryptophan is present in the cell, two tryptophan molecules serve as co-repressor and bind to the trp repressor. This binding activate the inactive repressor, the apo-repressor, to bind to the trp operator. Binding of the tryptophan-repressor complex at the operator prevents the RNA polymerase from binding the downstream genes and thus, presents their transcription. Here, tryptophan serve as a corepressor and inhibits the expression of genes not by direct binding to DNA but instead indirectly regulates gene expression by binding to repressors. Thus, In tryptophan operon, a repressor consists of co-repressor (tryptophan) and apo-repressor (protein). Correct option is C.

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