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B
Spleen
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C
Bone marrow
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D
None of the above
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Solution
The correct option is C Bone marrow
B cell activation occurs in the secondary lymphoid organs, such as the spleen and lymph nodes.
In mammals, B cells mature in the bone marrow, then they migrate through the blood to secondary lymphoid organs, which receive a constant supply of antigen through circulating lymph. Hence, in Bone marrow B cells matures.