Question

In which of the following cases, Hoffmann product is the major product?

• A.
• B.
• C.
• D.

Answer 1

Answer: (A), (B), (C), (D)

The correct options are
A
B
C
D

Hoffmann products i.e less substituted alkene can be possible when:

1. There is a weak leaving group like F because in this case carbanion transition state is formed which results in less substituted alkene.
2. Hoffman elimination for quaternary ammonium salts.
3. When there is a large bulky base, as in this case it abstracts less hindered hydrogen which results in less substituted alkene.