Question

In which of the following process ATP synthase channel produces ATP?

• A. Glycolysis
• B. Kerbs cycle
• C. Chemiosmosis
• D. (B) and (C) only
• E. (A), (B) and (C)

Answer 1

Answer: (C)

Chemiosmosis

Glycolysis and Krebs cycle form total 4 ATPs by substrate level phosphorylation wherein direct transfer of phosphate group to ADP or GDP during chemical reactions leads to synthesis of ATP/GTP. Oxidative phosphorylation is the process wherein oxidation of reducing equivalent generate energy to drive ATP synthesis. Chemiosmosis includes use of proton gradient generated across the inner mitochondrial membrane, during transfer of electrons from NADH and FADH${}_2$ to O${}_2$, to drive ATP synthesis on ATP synthase channel. Since inner mitochondrial membrane is impermeable to protons; protons can re-enter the matrix only through proton-specific channels (F${}_0$) of ATP synthase only.

Therefore, the correct answer is option C.