Question

In which of the following reaction of glycolysis, a molecule of water is removed from the substrate?

• A. Fructose-6-phosphate$\to$fructose 1,6-bisphosphate
• B. 3-Phosphate glyceraldehyde$\to$1,3-bisphosphoglyceric acid
• C. PEP$\to$ pyruvic acid
• D. 2-Phosphoglycerate$\to$ PEP
• E. Glucose$\to$glucose6-phosphate

Answer 1

Answer: (D)

2-Phosphoglycerate$\to$ PEP

During the formation of phosphoenol pyruvate (PEP) from 2-phosphoglycerate, a water molecule is eliminated. This reaction is catalysed by the enzyme enolase. This is a step of glycolysis. This reaction takes place in the cytoplasm.

Thus, the correct answer is option D.