In which of the following reactions of glycolysis, a molecule of water is removed from the substrate?
A
Glucose → Glucose-6-phosphate
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B
Fructose-6-phosphate → Fructose-1,6 bisphosphate
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C
2-phosphoglycerate → Phosphoenol pyruvate
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D
Phosphoenol pyruvate → Pyruvate
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Solution
The correct option is C 2-phosphoglycerate → Phosphoenol pyruvate Options A and B represent the addition of phosphate group to glucose and fructose 6 phosphates respectively. Option D represents dephosphorylation of phosphoenolpyruvate into pyruvate. Dehydration of 2-phosphoglycerate to phosphoenolpyruvate includes reversible removal of a molecule of water from 2-phosphoglycerate.