Question

In which of the following situations, there is risk of erythroblastosis foetalis

• A. Mother $R{h}^{+}$, father $R{h}^{+}$
• B. Mother $R{h}^{-}$, father $R{h}^{-}$
• C. Mother $R{h}^{-}$, father $R{h}^{+}$
• D. Mother $R{h}^{+}$, father $R{h}^{-}$.

Answer 1

Answer: (C)

Mother $R{h}^{-}$, father $R{h}^{+}$

C. Mother Rh-, father Rh+

EXPLANATION: Erythroblastosis fetalis is associated with Rh and ABO blood group. This disease may develop when a woman with Rh-negative blood is impregnated by a man with Rh-positive blood and then they conceive Rh-positive fetus. The Rh-positive foetus in the second pregnancy may trigger antibody reaction in the mother, whose antibodies attack and destroy the Rh+ erythrocytes of the foetus.