Question

In which of the following substrate phosphorylation does not occur?

• A. 1, 3-biphosphoglyceric acid $⟶$ 3 phosphoglyceric acid
• B. Glucose 6-phosphate $⟶$ Fructose 6-phosphate
• C. Succinyl CoA $⟶$ Succinic acid
• D. Phosphoenol pyruvic acid $⟶$ Pyruvic acid

Answer 1

The correct option is B Glucose 6-phosphate $⟶$ Fructose 6-phosphate

Phosphorylation is the process of adding a phosphate group to adenosine triphosphate (ADP) to form the adenosine triphosphate (ATP) by the enzyme kinase.

A. 1,3- biphosphoglyceric acid + ADP $\to$ 3- phosphoglyceric acid + ATP. It is substrate phosphorylation.

B. No phosphate group is added in Glucose 6-phosphate$\to$ 3 phosphoglyceric acid.

C. Succinyl- CoA + H${}_2$O + GDP/ADP $\to$ Succinate + CoA + GTP/ATP.

D. Phosphoenol pyruvic acid + AMP + P~P $\to$ Pyruvic acid +ATP + H${}_3$PO${}_4$.

Hence, the correct answer is 'Glucose 6- phosphate $\to$ Fructose 6- phosphate'.