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Question

In which of the following the pyrophosphate bond of ATP is broken down and linkage takes place between two molecules?

A
Isomerases
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B
Lyases
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C
Transferases
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D
Ligases
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Solution

The correct option is D Ligases
In Ligases the pyrophosphate bond of ATP is broken down and linkage takes place between two molecules.
Ligases catalyse the joining together of two molecules coupled with the hydrolysis of a pyrophosphate bond in ATP or a similar triphosphate.
Ligases (synthetases) catalyse reactions in which the pyrophosphate bond of ATP is broken down, and linkage takes place between two molecules.
The following bonds are formed by these enzymes.
CO,CS,CN and CC

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