Question

In which stage of the cell cycle are histone proteins synthesised in an eukaryotic cell ?

• A. G2- stage of prophase
• B. S-phase
• C. Entire prophase
• D. Telophase

Answer 1

The correct option is B S-phase

Histone protein is synthesized during S Phase of interphase. Interphase involves 3 phases:-

1. G${}_1$ phase.
   
2. S phase.
   
3. G${}_2$ phase.

However It is important to note that protein synthesis takes place in all three phases of interphase. Some proteins are synthesized in G${}_1$ Phase while other like tubulin protein is synthesized in G${}_2$ phase. However, synthesis of Histone protein takes place in S phase.

Thus the correct answer is 'S-phase.'