Question

In Wobble hypothesis, the pairing of the tRNA anticodon with the mRNA codon proceeds from

• A. 5'-3' end
• B. 3'-5 end
• C. Bidirectional
• D. None of the above

Answer 1

Answer: (A)

5'-3' end

Wobble hypothesis states the degeneracy of the genetic code. The pairing of the third base varies according to the base at the third position, for example, G may pair with U. The conventional pairing (A = U, G = C) is called Watson-Crick pairing and the second abnormal pairing is called wobble pairing.