Individual with solid symobol is sufferer of a genetic disease due to recessive autosomal allele. You would counsel a couple explaining the probability of their grandchildren to have the disease is

0 %

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25 %

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50 %

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100 %

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Solution

The correct option is C $50 %$
This is a pedigree chart used to study the pattern of inheritance.

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Q. A pedigree chart of a family with an autosomal recessive disease Z is given. Assume that inheritance is Mendelian, and that all individuals with homozygous recessive genotype have the disease. Circles in the pedigree represent females and squares represent males. Filled shapes indicate affected individuals, while unfilled shapes indicate unaffected individuals. If J does not have the recessive allele, the probability that I is a 'carrier of disease Z' is?

Q. Recessive mutations in some rare genetic disorders can manifest as disease. A couple had four sons and four daughters, of which two sons developed such a genetic disorder. The parents did not manifest disease symptoms. Further studies shows that this disease affects only males. If genes

P

(dominant allele) and

p

(recessive allele) are involved in this disorder, identify the correct statement from the options given below.

Q. In a random mating population, frequency of disease causing recessive allele is 80%. What would be the frequency of carrier individual in population?

Regarding the assertion and reason, choose the correct option.

Assertion [A]: A genetic disease that affects only one parent can have 50% chance of affecting the child.
Reason [R]: An autosomal dominant defective allele can cause a disease even in heterozygous condition.

Q. This is a pedigree for autosomal recessive disease albinism (aa). What is the probability of II – 1 being homozygous normal?

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Individual with solid symobol is sufferer of a genetic disease due to recessive autosomal allele. You would counsel a couple explaining the probability of their grandchildren to have the disease is

The correct option is C 50%This is a pedigree chart used to study the pattern of inheritance.

The correct option is C $50 %$
This is a pedigree chart used to study the pattern of inheritance.