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Question
Infective stage of Plasmodium that infects human beings is
Infective stage of Plasmodium that infects human beings is
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Solution
The correct option is B Sporozoite
The human infection begins when an infected female anopheles mosquito bites a person and injects infected with sporozoites saliva into the blood circulation. That is the first life stage of plasmodium (stage of infection). The next stage in malaria life cycle is the one of asexual reproduction that is divided into different phases: the pre- erythrocytic (or better, exoerythrocytic) and the erythrocytic phase. Within only 30- 60 minutes after the parasites inoculation, sporozoites find their way through blood circulation to their first target, the liver. The sporozoites enter the liver cells and start dividing leading to schizonts creation in 6- 7 days. Each schizont gives birth to thousands of merozoites (exoerythrocytic schizogony) that are then released into the blood stream marking the end of the exoerythrocytic phase of the asexual reproductive stage. Merozoites released into the blood stream, are directed towards their second target, the red blood cells (RBCs). As they invade into the cells, they mark the beginning of the erythrocytic phase. The first stage after invasion is a ring stage that evolves into a trophozoite. The next cellular stage is the erythrocytic schizont (initially immature and then mature schizont). Each mature schizont gives birth to new generation merozoites (erythrocytic schizogony) that, after RBCs rupture, are released in the blood stream in order to invade other RBCs. This is when parasitaemia occurs and cinical manifestations appear.
The human infection begins when an infected female anopheles mosquito bites a person and injects infected with sporozoites saliva into the blood circulation. That is the first life stage of plasmodium (stage of infection). The next stage in malaria life cycle is the one of asexual reproduction that is divided into different phases: the pre- erythrocytic (or better, exoerythrocytic) and the erythrocytic phase. Within only 30- 60 minutes after the parasites inoculation, sporozoites find their way through blood circulation to their first target, the liver. The sporozoites enter the liver cells and start dividing leading to schizonts creation in 6- 7 days. Each schizont gives birth to thousands of merozoites (exoerythrocytic schizogony) that are then released into the blood stream marking the end of the exoerythrocytic phase of the asexual reproductive stage. Merozoites released into the blood stream, are directed towards their second target, the red blood cells (RBCs). As they invade into the cells, they mark the beginning of the erythrocytic phase. The first stage after invasion is a ring stage that evolves into a trophozoite. The next cellular stage is the erythrocytic schizont (initially immature and then mature schizont). Each mature schizont gives birth to new generation merozoites (erythrocytic schizogony) that, after RBCs rupture, are released in the blood stream in order to invade other RBCs. This is when parasitaemia occurs and cinical manifestations appear.
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