Question

Inhibition of succinate dehydrogenase by malonate is an example of

• A. Non-competitive inhibition
• B. Competitive inhibition
• C. Allosteric inhibition
• D. Negative feed back

Answer 1

Answer: (B)

Competitive inhibition

An inhibitor is similar in shape to the usual substrate for the enzyme thus, it competes with the substrate for the active site. Malonate is a competitive inhibitor. It inhibits the enzyme succinate dehydrogenase. Malonate binds to the active site of this enzyme without reacting and competes with succinate which is the usual substrate of the enzyme.

So, the correct answer is 'Competitive inhibition'.