Insulin increases glucose uptake in all of the following structures, except

Cardiac muscle.

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Skeletal muscle.

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Adipose tissue.

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Intestinal mucosa.

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Solution

The correct option is D Intestinal mucosa.
Insulin mediates glucose uptake into adipose tissue and skeletal muscle through GLUT4 glucose transporters. Since this stimulates glucose uptake into muscle through increased glucose transporters. During this process, adipose tissue cells are involved in insulin-stimulated translocation. However, there are some tissues that do not require insulin for efficient uptake of glucose like the brain, liver and intestinal mucosa. Thus, the correct answer is option D.

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