The correct option is A Diabetes
The failure to make insulin or to respond to it constitutes diabetes mellitus. Insulin is made by the beta cells in the islets of Langerhans in the pancreas. If the beta cells degenerate, the body cannot make enough insulin on its own and type I diabetes results. A person with this type of diabetes must inject exogenous insulin (insulin from sources outside the body). In type II diabetes, the beta cells produce insulin, but cells throughout the body do not respond normally to it.